Tadalafil: long-term Effects large undocumented, discussion risks with Doctor.
Tadalafil (tadalafil) is a medicine that is used primarily to treat erectile dysfunction (ED) and erectile dysfunction associated with benign prostate disease (BPH). However, like many medications, it can have long-term side effects. Some of the possible long-term side effects include:
1. Cardiovascular effects
Arterial hypertension: in some rare cases, it has been associated with a slight increase in blood pressure. This is particularly worrying for patients who already have cardiovascular problems or are susceptible to hypertension.
Cardiovascular events: although the evidence is inconclusive, there are studies suggesting a possible increase, albeit very small, in the risk of serious cardiovascular events such as myocardial infarction or stroke with prolonged use.
2. Effects on the visual system
Changes in vision: some patients have reported changes in vision, such as bluish vision (cyanopsia). This is due to inhibition of a specific enzyme in the eye called phosphodiesterase-6 (PDE-6). Although in most cases it is reversible, it can be a nuisance and, in extreme cases, affect normal visual ability.
3. Effects on the nervous system
Chronic headache: may cause persistent headaches in a small percentage of patients taking the medication in the long term. These headaches may vary in intensity and frequency, and in some cases may affect the patient's quality of life.
Anxiety and sleep disorders: there have also been reports of anxiety and changes in sleep patterns, which could be due to the drug's interaction with the body's nervous and hormonal systems.
4. Effects on other organs
Liver problems: in very rare cases, a possible impact on liver function has been suggested. This usually manifests through changes in liver enzyme levels in blood tests.
Renal effects: although less common, concerns have been raised about a possible effect on renal function with prolonged use and in patients at pre-existing risk of kidney disease.
It is important that patients taking tadalafil in the long term are monitored regularly by a doctor. The doctor should assess the balance between the benefits of treatment for the underlying medical condition (DE or BPH) and possible side effects. In addition, patients should inform their doctor immediately if they experience any abnormal or worrying symptoms during treatment.