Tadalafil 5 mg (Cialis) for Treating Male ED.
Guía de Salud Masculina
tadalafil is a drug used to treat conditions such as erectile dysfunction (ED).
1. Pharmacological effects
1、mechanism of action
- Tadalafil promotes penile erection by inhibiting phosphodiesterase 5 (PDE5), increasing cyclic guanosine (cGMP) levels in the corpus cavernosum, relaxing smooth muscles, and blood flowing into penile tissue.
2、pharmacodynamic characteristics
- Tadalafil has a relatively long time of action, generally taking effect within 30 minutes to 2 hours after taking, and the effect can last for about 36 hours, which is different from other short-acting drugs for the treatment of erectile dysfunction.
2. Information related to the 5 mg dose
1、therapeutic use
- 5 mg of tadalafil is usually used in a once-daily low-dose long-term treatment regimen. This low-dose long-term use helps improve the blood supply to the corpus cavernosum. For some patients with mild to moderate erectile dysfunction, it may gradually improve erectile function and, to a certain extent, improve the patient's quality of sexual life.
- In addition to erectile dysfunction, it can also be used in some cases to treat lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH) because it relaxes the smooth muscle of the prostate and bladder neck and reduces symptoms such as difficulty urination.
2、precautions for use
applicable population：
- Not all patients are suitable for use, and it is contraindicated for those allergic to tadalafil; it is strictly prohibited for patients who are taking any form of organic nitrates (such as nitroglycerin) because the combination of nitrates with tadalafil can cause blood pressure to drop sharply and may be life-threatening.
adverse reactions：
- Common adverse reactions include headache, indigestion, back pain, muscle pain, flushing, etc. If any discomfort occurs during the use of 5 mg of tadalafil, seek medical attention promptly.
interactions with other medicinal products：
- Tadalafil is mainly metabolized by cytochrome P4503A4 (CYP3A4) in the liver. Certain drugs such as ketoconazole and ritonavir will increase the blood concentration of tadalafil and increase the risk of adverse reactions. If co-use is necessary, the dose of tadalafil should be adjusted.
The use of tadalafil 5 mg should be carried out under the guidance of a doctor. The doctor will comprehensively judge whether it is suitable for use and determine the course of use based on the patient's specific health condition, medical history and other drugs being taken.