cialis 10mg,CIALIS 10mg: An Overview
Cialis (tadalafil) 10mg is a medication used to treat erectile dysfunction (ED) and also symptoms of benign prostatic hyperplasia (BPH).
1. Mechanism of action for ED
- Tadalafil inhibits the enzyme phosphodiesterase type 5 (PDE5). In the penis, this leads to an increase in the levels of cyclic guanosine monophosphate (cGMP).
- Elevated cGMP causes smooth muscle relaxation in the penile arteries and corpus cavernosum, allowing increased blood flow into the penis, which is necessary for achieving and maintaining an erection.
2. Use for BPH
- In the context of BPH, tadalafil helps to relax the smooth muscle in the prostate and bladder neck, which improves urinary symptoms such as difficulty in starting urination, weak urine flow, and the need to urinate frequently.
3. Dosage and administration
- The 10mg dose is one of the common dosages. It is typically taken as needed for ED, usually about 30 minutes to 12 hours before sexual activity (although some effect may be seen as early as 16 minutes).
- For the treatment of BPH, it may be taken once daily.
- It should be taken orally with a glass of water, and can be taken with or without food.
4. Precautions and side effects
- Precautions:
- Tadalafil should not be used in combination with nitrates (e.g., nitroglycerin) as this can cause a significant and potentially dangerous drop in blood pressure.
- People with certain heart conditions, such as recent myocardial infarction or unstable angina, should use it with caution.
- Side effects:
- Common side effects may include headache, indigestion, back pain, muscle aches, flushing, and nasal congestion. Less common but more serious side effects can include sudden vision or hearing loss, although these are rare.
It is important that Cialis is used under the supervision of a healthcare provider.